{"id":464,"date":"2018-07-03T22:49:06","date_gmt":"2018-07-03T22:49:06","guid":{"rendered":"http:\/\/molecularmitomd.com\/?page_id=464"},"modified":"2024-06-08T16:01:36","modified_gmt":"2024-06-08T16:01:36","slug":"incidental-findings","status":"publish","type":"page","link":"http:\/\/molecularmitomd.com\/?page_id=464","title":{"rendered":"Incidental Findings"},"content":{"rendered":"<p>Genetic testing is designed to determine causes or factors underlying your\/your child\u2019s illness, in<br \/>\norder words finding that are relevant to the reason why testing was performed. However,<br \/>\nsometimes the genetic results indicate findings that are likely unrelated to the reason that testing<br \/>\nwas performed. These so called \u201cincidental findings\u201d can include, but are not limited to, the<br \/>\nfollowing:<\/p>\n<ol>\n<li>The presence of another condition that you\/your child may have.<\/li>\n<li>An increased risk to develop certain conditions, for example certain cancers, and heart or<br \/>\nbrain disease.<\/li>\n<li>\u00a0An increased risk related to certain drugs. For example, that a given drug, if taken, may<br \/>\nlead to toxic blood levels, severe bleeding, or even sudden death.<\/li>\n<li>Bullets 1 to 3 above could also apply to one or more relatives if they carry the same<br \/>\ngenetic change(s).<\/li>\n<li>Genetic \u201cblood\u201d relationship between the parents may be identified by testing.<\/li>\n<li>Non-paternity may be identified by testing if parental samples are provided.<\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p>When you were originally consented for genetic testing, you should have been given the<br \/>\nopportunity to \u201copt-out\u201d of receiving information on incidental findings. If you continue to wish<br \/>\nto opt-out, or if you change your mind, please contact your physician so that incidental findings<br \/>\nwill not be discussed. However, even if you do opt out, you will be told about cross-over<br \/>\nfindings that may be relevant to the disease being tested, as well as relevant to other issues. For<br \/>\nexample, sequence variants in some genes can predispose (increase the risk) towards migraine,<br \/>\nseizures, and abnormal heart rhythms. If your child has migraine, you will also learn about<br \/>\npotential risks for seizures and abnormal heart rhythms.<\/p>\n<p>&nbsp;<\/p>\n<p>Despite the focus being on the primary illness, sequence re-analysis as part of the<br \/>\nComprehensive Service is likely to identify one or more potential incidental findings NOT listed<br \/>\non the official report from the testing laboratory.<br \/>\nPlease consider among the two below choices:<\/p>\n<p>____ I wish to receive ALL results that my physician and\/or Dr. Richard Boles believe<br \/>\nmay be directly related to my\/my child\u2019s health.<\/p>\n<p>____ I do NOT wish to receive the above results that my physician and\/or Dr. Richard Boles\u00a0believe<br \/>\nare likely not directly related to the reason for which testing was performed.<\/p>\n<p><strong>Be sure to discuss your preference with your physician.<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Genetic testing is designed to determine causes or factors underlying your\/your child\u2019s illness, in order words finding that are relevant to the reason why testing was performed. However, sometimes the genetic results indicate findings that are likely unrelated to the reason that testing was performed. These so called \u201cincidental findings\u201d can include, but are not [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-464","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"http:\/\/molecularmitomd.com\/index.php?rest_route=\/wp\/v2\/pages\/464","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/molecularmitomd.com\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/molecularmitomd.com\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/molecularmitomd.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/molecularmitomd.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=464"}],"version-history":[{"count":2,"href":"http:\/\/molecularmitomd.com\/index.php?rest_route=\/wp\/v2\/pages\/464\/revisions"}],"predecessor-version":[{"id":642,"href":"http:\/\/molecularmitomd.com\/index.php?rest_route=\/wp\/v2\/pages\/464\/revisions\/642"}],"wp:attachment":[{"href":"http:\/\/molecularmitomd.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=464"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}